A L T H O U G H - D E S P I T E - I N S P I T E O F
1. We can make contrasts by connecting two sentences with although.
2. Despite & in spite of have the same meaning but the usage is different.
Although + sentence + sentence *** Although it was raining heavily, we kept on playing football.
Despite + noun *** Despite heavy rain, we kept on playing football.
In spite of + gerund + sentence *** In spite of raining heavily, the rain was giving pleasure to me .
In spite of + adj. + noun *** In spite of heavy rain, we kept on playing football.